Which of the following is a requirement for the immediate use provision?

The immediate use provision is designed to allow for the preparation of sterile compounds in situations where the need for rapid administration is critical, such as in emergencies. One of the key requirements of this provision is that there should be no more than two entries into one container. This restriction helps minimize the risk of contamination, ensuring the compounded preparation remains sterile while facilitating its use in urgent situations.

The other options present requirements or scenarios that are not aligned with the immediate use provision. For instance, allowing a compounding process to exceed one hour is counter to the intention of immediate use, which focuses on prompt delivery and use. Furthermore, hazardous drugs typically require stricter handling and compounding standards due to their significant risks, which is not consistent with immediate use scenarios. Lastly, compounding in a non-sterile environment would not maintain the necessary sterility for immediate use, which must occur under appropriate conditions to prevent contamination. Therefore, the correct answer emphasizes the critical limit on container entries to uphold safety and sterility in urgent compounding situations.