Immediate remediation of Active (Viable) Air Sampling CFUs is required if which types of microbes are identified?

Immediate remediation of Active (Viable) Air Sampling CFUs is required when Gram-negative rods and coagulase-positive staphylococcus are identified due to the potential severity of infections they can cause. Gram-negative rods are known for their virulence and ability to cause significant health complications, especially in immunocompromised patients. Coagulase-positive staphylococcus, particularly Staphylococcus aureus, can lead to serious infections, including skin and soft tissue infections, pneumonia, and bloodstream infections.

Identifying these organisms in a sterile compounding environment signifies a higher risk, requiring prompt investigation and remediation to ensure patient safety and compliance with regulatory standards. The presence of these microbes indicates a breach in aseptic technique or contamination processes that need immediate attention to restore an environment suitable for sterile product preparation.

In contrast, other options may involve microbes that pose lower risks or require less immediate action, thus underscoring the critical need for addressing the presence of Gram-negative rods and coagulase-positive staphylococcus efficiently and meticulously.