How should opened single-dose ampules be handled?

Opened single-dose ampules should not be stored for any amount of time once they have been accessed. This guideline is based on the sterility and integrity of the medication contained within the ampule. Once an ampule is opened, the internal environment is exposed to potential contaminants from the air and surrounding surfaces. Unlike multidose vials, which are designed to allow for multiple uses under specific conditions, single-dose ampules are intended for immediate use to ensure patient safety and drug efficacy. Therefore, to maintain stringent sterility standards and prevent contamination, any unused portion of an opened single-dose ampule must be discarded immediately and should not be stored for later use, regardless of the time frame.